TriNutra’s cold-pressed black cumin oil harnessed for healthy scalp and skin

08 Sep 2022 --- A human clinical study reveals a decrease of nearly 60% in erythema (redness) scores and a 30% decrease in participants who had mild to moderate seborrhea of the scalp when using TriNutra’s cosmetic black seed oil (BSO) extract, B’utyQuin.

The study published in SOFW Journal demonstrates that B’utyQuin’s constituents, including 3% thymoquinone (TQ) and low free fatty acids (FFA), act synergistically to maximize the mitochondrial functions, metabolism, energy (ATP) production as well as anti-inflammatory, antioxidant and antimicrobial benefits.

“Not only did B’utyQuin improve symptoms of seborrheic dermatitis such as redness, itchiness, scaling and flaking of the scalp, but it also had soothing properties and reduced scalp oiliness,” says Morris Zelkha, CEO at TriNutra.

The single-center study involved male and female subjects aged between 18 and 65 years old to test BSO’s antimicrobial effects on microorganisms such as Malassezia furfur, Candida albicans and Staphylococcus aureus, often associated with such disorders.

Clinical research to establish the efficacy, safety and compatibility of BSO as an active topical ingredient for the scalp showed its ability to treat symptoms associated with seborrheic dermatitis.

Black seed oil derived from Nigella sativa has been used for medicinal and beauty routines since the ancient Egyptian pharaohs and queens. (Credit: TriNutra)Ancient rituals
The annual flowering plant, Nigella sativa, in the family Ranunculaceae native to South and West Asia, its black seeds and oil derived from them have been used for medicinal and beauty routines since the ancient Egyptian pharaohs and queens, like Nefertiti and Cleopatra, shares the company.

Black cumin oil has been used in traditional medicine for more than 2000 years in Eastern and Ayurvedic lineages. It was also used by Greek physicians to treat everything from headaches, general malaise, congestion, intestinal worms, toothache and more.

TriNutra’s cold pressed black cumin oil, is standardized to 3% TQ – a potent active molecule, and contains fatty acids like linoleic acid, oleic acid and palmitic acid. FFA level is kept very low (< 2%) to maintain high stability and quality.

Recently, BSO has been studied in vitro to determine the mechanisms responsible for skin disorders such as irritated, itchy, scaly skin and scalp and seborrheic dermatitis.

In a blinded, controlled clinical trial in subjects with mild to moderate seborrheic dermatitis, topical application of scalp serum with 5% B’utyQuin for 28 days resulted in “significant improvements” in scalp oiliness, irritation, itchiness, scaling and overall health of the scalp as compared to baseline.

Skin and hair health
Several benefits can be attributed to BSO, according to the research. In-vivo studies revealed anti-aging properties, including skin appearance brightening and smoothing, hydration, evening skin tone and surface. It also confirmed relief for seborrhea and dandruff, bettering scalp health.

Furthermore, in-vitro studies disclosed effects on key mitochondrial biogenesis and ATP production regulators. It can also inhibit NO and inflammatory cascade and protect DNA from UV damage.

“Regulating growth of S. aureus, C. albicans and M. furfur with the unique composition of black seed oil with 3% thymoquinone and low free fatty acid will play an important and long-term role in maintaining skin homeostasis,” Dr. Liki von Oppen-Bezalel, TriNutra’s business development director, said during the previous study on the phytochemical compound thymoquinone.

The study concluded that cold-pressed black seed oil standardized to 3% thymoquinone with low free fatty acids, is a safe option to strongly regulate the growth of key microorganisms influencing skin health and to assist in balancing the skin and gut microbiome.

Edited by Radhika Sikaria

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