Roelmi HPC launches anti-aging upcycled active ingredient for boosting skin elasticity

30 Mar 2022 --- Actives and functionals expert Roelmi Health & Personal Care (Roelmi HPC) has debuted Ener-GY plus, “a cell energizer active ingredient designed to optimize mitochondrial activation” for improving skin elasticity. The ingredient is made from upcycled active solvents rich in fruit oligo-elements and enzymatic biotechnology.

Andrea Maltagliati, market manager at Roelmi HPC, speaks with PersonalCareInsights, detailing Ener-GY plus’ impact on industry, enzymatic biotechnology and the importance of targeting mitochondrial reactions. 

“The cosmetic market is witnessing a real revolution regarding skin’s ‘micro’ world and the skin microbiota environment,” he says.

“Ener-GY plus performs an overall beneficial effect on the skin ecosystem, decreasing the cellular senescence by promoting a high cellular vitality.”  

Maltagliati advises the application of Ener-GY plus for “pro-aging skincare, microbiota care, revitalizing treatments and tired or stressed skin.” 

Clinical studies show that Ener-GY plus can prevent signs of skin fatigue and enhance complexion by improving the “skin elasticity, firmness and radiance.” Additionally, it has been proven to help balance the skin microbiota.   

Ener-GY plus supports mitochondrial biochemical pathways by providing the proper condition for trophic cell processes and metabolism. More specifically, it promotes ATP production (cellular respiration in mitochondria). 

Concerning the wider industry
Maltagliati says there is a cosmetic spotlight on caring for the microorganisms residing on the skin. This is to prevent “skin dysbiosis” and to achieve long-term well-being. 

“Ener-GY plus concur to take care of the global skin ecosystem, intended to keep the perfect balance for the skin microbiota survival,” continues Maltagliati. 

Additionally, Maltagliati explains that Ener-GY plus responds to the increasing demand for sustainable solutions. “Most of the energy is produced in these tiny organelles and is one of the most interesting targets still in the research phase for the cosmetic world,” shares Maltagliati.

Maltagliati describes Roelmi HPC  as targeting the development of the microbiome and environmentally friendly compounds for ecosystem and planetary well-being.  

Loss of cellular energy with age
“The decay of mitochondrial vitality is a major contributor to aging,” states Maltagliati.    

“As per the endosymbiosis theory, mitochondria are the evolution of eukaryotic primitive cells’ ability to produce energy by incorporating aerobic bacteria. They ensure cell survival, being the energy powerhouse where ATP production occurs.” 

He explains that recent studies show that young people have almost no mitochondrial damage compared to many damaged mitochondria in older people. 

“Furthermore, external factors concur to accelerate the production of free radicals. As a result, the cumulative damage to the mitochondria makes them less efficient at turning fuel into energy, and the number of mitochondria per cell reduces,” says Maltagliati.

Therefore, when skin cells lose energy, this can lead to a dull and tired complexion and hence signs of aging emerge. 

Roelmi HPC describes the effects of Ener-GY plus as “smiling skin.” This is because smiling, talking and eating causes muscles to repeatedly contract and lose skin elasticity.“The cosmetic market is witnessing a real revolution regarding skin’s “micro” world and the skin microbiota environment,” shares Maltagliati. 

What is enzymatic biotechnology?  
“In the case of the production process of Ener-GY plus, glucose and glycerin are used as substrates,” Maltagliati shares. 

“Glyceryl glucoside represents the main molecule used to produce energy when broken down into glucose and glycerin – glucose being a starting substrate in these energy mechanisms.”  

Additionally, Maltagliati says, only 100% biologically active water is used as a solvent. The active water is sourced from Mediterranean fruits. 

Maltagliati explains that in 1894, Emil Fischer was the first to propose a “lock and key” mechanism. This involved enzymes and their preferred substrate for low-energy reactions. 

“Cellular energy is one of the aspects linked to skin aging and our continuous research has led us in the direction of enzymatic synthesis products.” 

Importance of the mitochondria
The mitochondria is said to have various functions such as producing energy and providing metabolites for macromolecules, explains Maltagliati. 

The metabolic functions of mitochondria go beyond being the powerhouse of the cell. 

“Mitochondria catabolizes nutrients for energy, generates biosynthetic precursors for macromolecules and compartmentalizes metabolites to maintain redox homeostasis,” continues Maltagliati. 

“Most of the energy is produced in these tiny organelles and is one of the most interesting targets still in the research phase for the cosmetic world.”  

Microbiome start-up Sequential Bio has recently debuted its first in-vivo testing for the personal care industry. 

PersonalCareInsights also recently spoke with a research team examining how a robust microbiome could be the secret to healthy aging. 

By Venya Patel